Common Spay & Neuter Questions on Cats How Do You Know When Males Cats Can Be Neutered? By six to eight weeks of age, both testes have descended into the scrotum of the male cat and they can be neutered. How Often Do Female Cats Come Into Heat? They come into heat every two weeks. Siamese cats often breed year round. Each heat period varies in length, but typically lasts between five days and three weeks. She can experience repeated cycles every 12 to 22 days if not pregnant. Puberty in females, on average, occurs between 5 and 9 months of age. Pregnancy in cats lasts, on average, about 63 days. Cats that are spayed before their first heat rarely develop mammary tumors. Most mammary tumors are malignant. Litters on average consist of up to four kittens per litter and a typical queen can have two to three litters per year. She can have anywhere from 50 to 150 kittens in her lifetime.
Signs of females in heat are: excessive vocalization, rubbing her head and neck against people and objects, becoming very affectionate, rolling and squirming, making 'treading movements' with her back legs, and assuming the mating position - the rump in the air, tail deflected to the side and back arched downward.